ACP Backs Hormones for Vasomotor Symptoms in Menopause
Medscape reports that the American College of Physicians issued a guideline naming estrogen, with progestogen for women with a uterus, as first-line treatment for menopausal hot flashes and night sweats, based on high-level evidence. Nonhormonal options such as venlafaxine, gabapentin and fezolinetant follow as second- and third-line choices with low to moderate certainty evidence. An outside expert notes included trials were short, with a median of about 12 weeks.
Why it matters: Relevant to women experiencing hot flashes or night sweats during and after menopause, and to primary care clinicians and gynecologists who manage these symptoms.
A summary of another publisher's reporting, written with AI and checked automatically against the story. The reporting belongs to medscape.com. October 7, 2026.