ACP: Use hormone therapy as first-line treatment for menopausal vasomotor symptoms
Healio reports that the American College of Physicians issued new guidance in Annals of Internal Medicine recommending hormone therapy as first-line treatment for menopausal vasomotor symptoms, which affect up to 80% of women in perimenopause. SNRIs are suggested second-line, with SSRIs, gabapentin or neurokinin receptor antagonists third-line. An editorial notes open questions on when to start and how long to continue.
Why it matters: Relevant to women in perimenopause or menopause experiencing hot flashes or night sweats, and to the primary care and women's health clinicians who counsel them.
A summary of another publisher's reporting, written with AI and checked automatically against the story. The reporting belongs to healio.com. October 5, 2026.