Model predicts growth hormone therapy responses in children with short stature
Medical Xpress reports a retrospective, single-center study of 91 prepubertal Korean children with idiopathic short stature treated with growth hormone. Mean height percentile rose from 1.26 at baseline to 9.16 at follow-up, with wide individual variation. A model linked higher BMI, lower IGFBP-3 and shorter paternal height to greater predicted response. A web tool, GrowCast, is not yet validated; larger prospective studies are needed.
Why it matters: Relevant to parents and to the pediatric endocrinologists and referring clinicians who discuss growth hormone therapy for children with idiopathic short stature.
A summary of another publisher's reporting, written with AI and checked automatically against the story. The reporting belongs to medicalxpress.com. October 5, 2026.