Tirzepatide cuts fat mass by 35% while preserving skeletal muscle
News-Medical reports on a retrospective, real-world study of 122 adults with overweight or obesity, without type 2 diabetes, treated at two centers in Palermo, Italy. Alongside diet and activity advice, 24 weeks of tirzepatide was associated with fat mass falling 35.4% while skeletal muscle mass stayed stable. There was no control arm, and most participants were women.
Why it matters: Relevant to Maryland adults weighing medical weight loss, and to clinicians who refer them, interested in body-composition data from real-world tirzepatide care.
A summary of another publisher's reporting, written with AI and checked automatically against the story. The reporting belongs to news-medical.net. October 4, 2026.